Research & Publications [Dr. Manzoor Ahmad]

Research Papers

1. New α-glucosidase inhibitors and antibacterial compounds from Myrtus communis L. Atta-ur-Rahman, Muhammad Iqbal Choudhary, Farzana Shaheen, Manzoor Ahmad, Shamsun Nahar Khan, Shazia Anjum, US Patent Application submitted (Application # 11306345, filled December, 23, 2005).

2. M. Nisar, Inamullah khan, Manzoor Ahmad. Molecular docking of Taxawallin I to β-tubulin: anticancer taxoid from Taxus wallichiana Zucc.Journal of Enzyme Inhibition and Medicinal Chemistry. (accepted, 2008)

3. Waqar Ahamd, Li Bo, Yulin Deng, Manzoor Ahmad, Zafar Iqbal, Zahida Parveen, Khalid Saeed. Analysis of biomarker for the cross-linker of formaldehyde with bovine serum albumin peptide. Chinese Science Bulletin. (accepted, 2008)

4. Manzoor Ahmad, Muhammad Zeeshan, Noureen Khan, Sarfaraz Ahmad Nawaz, Muhammad Iqbal Choudhary and Farzana Shaheen. In vitro enzyme inhibition activities of Myrtus communis L., Journal of Enzyme Inhibition and Medicinal Chemistry,  (accepted 2008)

5. Muhammad Arfan, Rasool Khan, Murad Ali, Sahzia Ajum, Manzoor Ahmad, and Muhammad Iqbal Choudhary. Antileishmanial and Anti microbial Activities of 2,3-disubstituted-3H-quinazolin-4-one Derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry,  (Accepted 2008)

6. Mansoor Ahmad, Noor Muhammad, Manzoor Ahmad, Muhammad Zeeshan, Mahjabeen, Noor Jehan, Zahid Khan, Saeed ul Hassan, and Farzana Shaheen. Antifungal and antibacterial activities of Datisca cannabina Linn., Journal of Enzyme Inhibition and Medicinal Chemistry,  23(3), 386-390, 2008.

7. Manzoor Ahmad, Noureen Khan, Muhammad Zeeshan, Shamsun Nahar khan, Muhammad Iqbal Choudhary and Farzana Shaheen. New antioxidant and α-glucosidase inhibitors from Myrtus communis Linn., European Journal of Organic Chemistry,  (submitted 2008)

8. Manzoor Ahmad, Muhammad Zeeshan, Mahmud Tareq Hassan Khan, Habib Ahmad and Farzana Shaheen. Norditerpenoid Alkaloids of Aconitum laeve Royle and their enzyme inhibition activities. European Journal of Organic Chemistry, (submitted 2008)

9. Manzoor Ahmad, Waqar Ahamd, Mansoor Ahmad, Obaidullah, Muhammad Zeeshan, and Farzana Shaheen. Norditerpenoid alkaloids from the roots of Aconitum heterophyllum Wall. Journal of Enzyme Inhibition and Medicinal Chemistry. (in press, 2008)

10. Manzoor Ahmad, Waqar Ahamd, Saleemullah Khan, Mansoor Ahmad, Muhammad Nisar, Muhammad Zeeshan, and Farzana Shaheen. Antibacterial Pentacyclic Triterpenoids from Myricaria elegans. Journal of Enzyme Inhibition and Medicinal Chemistry. (in press, 2008)

11. Mansoor Ahmad, Noor Muhammad, Manzoor Ahmad, Muhammad Arif Lodhi, Mahjabeen, Noor Jehan, Zahid Khan, Rosa Ranjit, Farzana Shaheen, and Muhammad Iqbal Choudhary. Urease Inhibitor from Datisca cannabina Linn. Journal of Enzyme Inhibition and Medicinal Chemistry. 23(3), 386-390, 2008

12. Muhammad Nisar, Obaidullah, Manzoor Ahmad, Muhammad Arif Lodhi, Farzana Shaheen, and Muhammad Iqbal Choudhary. New diterpenoid Alkaloids Aconitum heterophyllum Wall: Selective Butyrylcholinestrase Inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. (in press, 2008)

13. Muhammad Nisar, Obaidullah, Manzoor Ahmad, Farzana Shaheen, and Viqaruddin Ahmad. Norditerpenoid Alkaloids from the roots of Aconitum heterophyllum Wall. Bioorganic and Medicinal Chemistry Letter, (Submitted, 2008)

14. Muhammad Liaqat Raza, Muhammad Zeeshan, Manzoor Ahmad, Farzana Shaheen, Shabana U. Simjee. Toxicity testing behavior assessment of anticonvulsant fraction isolated from Delphinium specie.Journal of Pharmacological and Toxicological Methods 58(2) 152 (2008)

15. Farzana Shaheen, Liaqat Ali, Manzoor Ahmad, Muhammad Zeeshan, Shabana U. Simjee, and Muhammad Arfan.  Anti epileptic activity of various fractions and isolation of new norditerpenoid alkaloid from Delphinium kohatanese Munz, Journal of Enzyme Inhibition and Medicinal Chemistry, (submitted 2008)

16. Farzana Shaheen, Manzoor Ahmad, Shamsun Nahar khan, Syeda Samreen Hussain, Shazia Anjum, Bahodir Tashkhodjaev, Kambarali Turgunov,  Mukhlis N. Sultankhodzhaev, Muhammad Iqbal Choudhary, and Atta-ur-Rahman. New α-glucosidase inhibitors and antibacterial compounds from Myrtus communis Linn., European Journal of Organic Chemistry, 2371-2377 (2006)

17. Farzana Shaheen, Muhammad Zeeshan, Manzoor Ahmad, Shazia Anjum, Shamshir Ali, Hong-Kun Fun, Muhammad Iqbal Choudhary, and Atta-ur-Rahman. Norditerpenoid alkaloids from Delphinium nordhagenii. Journal of Natural Product, 69, 823-825 (2006)

18. Anwar-ul Hassan Gilani, Abdul Jabbar Shah, Manzoor Ahmad and Farzana Shaheen. Antispasmodic effect of Acorus calamus Linn., is mediated through calcium channel blockade.  Phytotheraphy Research, 20, 1080-1084 (2006)

19. Manzoor Ahmad, Shamsher Ali, Farzana Shaheen, Shazia Anjum, and M. Iqbal Choudhary. 14-Acetyl-20-Ethyl-1, 8-Dihydroxy-16, 18-Dimethoxylycoctonine. Acta Crystallographica, (2006). E62, 01428-01430.

20. Manzoor Ahmad, Farzana Shaheen, Bahodir Tashkhodjaev, Kambarali Turgunov,  Mukhlis N. Sultankhodzhaev, Muhammad Iqbal Choudhary, and Atta-ur-Rahman. Chemical Constituents of Myrtus communis L. Chemistry of Natural Compounds,  3, 277, (2006) (Russ)

21. Farzana Shaheen, Manzoor Ahmad, Mahmood Tareq Hassan Khan, Saima Jalil, Asma Ejaz, Mukhlis N. Sultankhodjaev, Muhammad Arfan, M. Iqbal Choudhary and Atta-ur-Rahman.   Alkaloids of Aconitum laeve Royle and their anti inflammatory, antioxidant and tyrosinase inhibition activities. Phytochemistry, 66, 935-940, (2005)

22. Taous khan, Mansoor Ahmad, Muhammad Nisar, Manzoor Ahmad, Muhammad Arif Lodhi and Muhammad Iqbal Choudhary. Enzyme inhibition and radical scavenging activities of aerial parts of Paeonia emodii Wall, Journal of Enzyme Inhibition and Medicinal Chemistry, 20(3), 245-249, (2005).

23. Somia Khattak, Saeed-ur-Rehman, Waqar Ahmad, Hameed Ullah Shah, Anwar Ali and Manzoor Ahmad, Biological Effects of Indigenous Medicinal Plants Curcuma longa Linn., and Alpinia galanga. Fitoterapia76, 254-257, (2005).

24. S. Khattak, Saeed-ur-Rehman, H. U. Shah, T. Khan, Manzoor Ahmad. In-vitro Enzyme inhibition activities of crude ethanolic extracts derived from medicinal plants of Pakistan, Natural Product Research,19, 567-571,(2005).

25. Ijaz Ahmad, Sarfraz Ahmad Nawaz, Nighat Afza, Abdul Malik, Itrat Fatima, Sher Bahadar Khan, Manzoor Ahmad, and M. Iqbal Choudhary, Isolation of Onosmins A and B, Lipoxygenase Inhibitors  from Onosma hispida  Chem. Pharm. Bull., 53(8), 907-910 (2005).

26. Mansoor Ahmad, Taous Khan, Muhammad Nisar, Muhammad Arif Lodhi, Waqar Ahmad, and Manzoor Ahmad. In vitro inhibition of Urease and a-Chymotrypsin by some selected indigenous Medicinal Plants. International Chemical, Pharmaceutical and Medical journal, 2(1), 179-181 (2005).

27. Waqar Ahmad, Mansoor Ahmad, Muhammad Nisar, Salimullah, Zafar Iqbal, Manzoor Ahmad, and Farzana Shaheen. Biological and Pharmacological Effects of Myricaria elegans Royle. International Chemical, Pharmaceutical and Medical journal, 2(1), 197-200 (2005).

28. Farzana Shaheen, Manzoor Ahmad, Shazia Anjum, M. Sukeri M. Yusof, Bohari Mohd. Yamin, Habib Ahmad, M. Iqbal Choudhary and Atta-ur-Rahman. [16β]-20-N-Ethyl-16, 18-Dimethoxy-1,8, 14-Trihydroxylycoctonin. Acta Crystallographica, E60, 0774-0776 (2004)

29. S. Khattak, Saeed-ur-Rehman, T. Khan, A. Ali, Manzoor Ahmad. Invitro Screening for Biological and Pharmacological Effects of Indigenous Medicinal Plants, Mentha logifolia and Aloe vera, J.  Chem. Soc. Pak. 26 (3), 248-251, (2004).

30. Mansoor Ahmad, Mehjabeen, Noorjahan, Noor Muhammad Shah, Manzoor Ahmad, Hyder Raza, Saeed khan, and Asif Bin Rehman. Results of rapid anti microbial sensitivity and toxicity test of the extracts of Swertia chirata, Symplocos racemosa and Solanum nigrum. International Chemical Pharmaceutical and Medical Journal, 1(2), 145-147 (2004). 

31. M. Iqbal Choudhary, Shamsher Ali, Shazia Anjum, Manzoor Ahmad, Azhar Abdul Rahman, Hoong-Kun Fun and Atta-ur-Rahman. Structure Reports of 4, 4, 14-Trimethyl-3α, 20-bis (methyl amino)-9,19-cyclo-5α-pregnan-16-0l. Acta Crystallographica, E59, 01751-01753 (2003).

32. Bashir Ahmad, Qasim Jan, Shumaila Bashir, Muhammad Nisar, Farzana Shaheen and Manzoor Ahmad. Pharmacological and Biological Investigation of Chenopodium murale Linn. Asian Journal of Plant Sciences, 2 (15-16): 1107-1111 (2003). 

33. Taous Khan, W. Ahmad, Manzoor Ahmad, Farzana Shaheen, M. Arfan, "Biological and Pharmacological Properties of Abroma augusta Linn. Seed Oil", Pak. J. Bio. Sci., 6 (13), 1142 – 1144, (2003). 

34. Waqar Ahmad, Taous Khan, Mansoor Ahmad, Manzoor Ahmad, Bashir Ahmad, Zafar Iqbal and Muhammad Arfan, Chemical Composition of Abroma augusta Linn. Seed Oil, Pakistan J. Biol. Sci., 6 (12), 1033 – 1034, (2003).

35. Waqar Ahmad, Bashir Ahmad, Manzoor Ahmad, Zafar Iqbal, Muhammad Nisar, and Mansoor Ahmad. In Vitro inhibition of acetylcholinesterase, butyrylcholinestrase and lipoxygenase by crude extract of Myricaria elagans Royle. Pak. J. Biol. Sci., 3(11), 1046-1049, (2003).

36. Ulubelen, A. H. Mericli, F. Mericli, U. Kolak, M. Arfan, Manzoor Ahmad and H. Ahmad. Norditerpenoid alkaloids from the roots of Aconitum laeve Royle. Pharmazie.57(6), 427-429, (2002).

37. Ulubelen, A. H. Mericli, F. Mericli, U. Kolak, M. Arfan, Manzoor Ahmad and H. Ahmad. Royleinine, A new Norditerpenoid alkaloid from Delphinium roylei Munz. Heterocycle, 53 (10), 2279-2283, (2000).

Abstracts

1. α-Glucosidase Inhibitors from Myrtus communis Linn. Manzoor Ahmad, Farzana Shaheen, Shams-un-Nahar Khan, Shazia Anjum, Muhammad Iqbal Choudhary, and Atta-ur-Rahman. First international Conference on Recent challenges in chemistry, Oral, (Abstract), pp. 43, November 1-3, 2006.
2. Antibacterial compounds from Myrtus communis Linn. Manzoor Ahmad, Farzana Shaheen, Shazia Anjum, Syeda Samreen Hussain, Mukhlis N. Sultankhodzhaev, M. Iqbal Choudhary and Atta-ur-Rahman. 10th international symposium on Natural product chemistry Poster, (Abstract), PO-009, pp, 115, January 6-9, 2006.
3. Chemical constituents from Chenopodium botrys Linn. M. Abdullah Al-Maruf, M. I. Choudhary, Manzoor Ahmad and Atta-ur-Rehman. 10th international symposium on Natural product chemistry Poster, (Abstract), PO-018, pp, 124, January 6-9, 2006.
4. Biological Activities of “Swertia cordata. Sirajuddin, Manzoor Ahmad, Sajidul Ghafoor, Anwar ul Haq, Ali Hazarat, Muhammad Irfan, Farzana Shaheen and Jahandar Shah. 10th international symposium on Natural product chemistry. Poster, (Abstract), PO-193, pp, 300, January 6-9, 2006.
5. Extraction of bioactive constituents from Delphinium nordhagenii. Muhammad Liaquat Raza, Humera Perveen, Muhammad Zeeshan, Liaquat Ali Malik, Manzoor Ahmad, Farzana Shaheen and Shabana U Simjee. 40th IUPAC Congress, Innovation in Chemistry Beijing China. Poster, (Abstract), 2-P-076, pp. 292, August 14-19, 2005
6. Active principle of bioactive constitute from Aconitum Violaceum. Muhammad Zeeshan, Manzoor Ahmad, M. Liaquat Raza, Humera Perveen, Tania Razvi, Huma Javed, Liaquat Ali Malik, Shabana U Simjee and Farzana Shaheen. AFASSA Symposium on Natural Products and Regional Meeting. Organized by HEJ Research Institute of Chemistry, International Center for Chemical Sceinces, University of Karachi, Karachi-75270. Poster, (Abstract), PO-18, pp, 33, July 25-27, 2005.
7. Antiepileptic activity of acetone fraction of Aconitum species. Humera Perveen, M. Liaquat Raza, M. Zeeshan, Manzoor Ahmad, Farzana Shaheen and Shabana U Simjee. AFASSA Symposium on Natural Products and Regional Meeting. Organized by HEJ Research Institute of Chemistry, International Center for Chemical Sceinces, University of Karachi, Karachi-75270. Poster, (Abstract), PO-11, pp, 26, July 25-27, 2005.
8. Anticonvulsant activity of Dns-Ii acetone fraction of Delphinium nordhagenii. M. Liaquat Raza, H. Perveen, M. Zeeshan, Manzoor Ahmad, Liaquat A. Malik, Tania Razvi, Farzana Shaheen and Shabana U Simjee. AFASSA Symposium on Natural Products and Regional Meeting. Organized by HEJ Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi-75270. Poster, (Abstract), PO-10, pp, 25, July 25-27, 2005
9. Swatinine, A New Norditerpenoid Alkaloid from Aconitum laeve Royle, and its Anti-inflammatory and Tyrosinase Inhibition studies on the Diterpenoid Alkaloids. Manzoor Ahmad, F. Shaheen, S. Jalil, M. T. H. Khan, M. I. Choudhary, and Atta-ur-Rehman. 9th international symposium on Natural product chemistry, Abstract, 10 (PO), pp. 115, January 10-13, 2004.
10. Biological activities of Myrtus communis Linn. Manzoor Ahmad, F. Shaheen,  M. I. Choudhary, S. Ali, S. Ahmad, S. M. Khudajzhave, T. Makhmoor and Atta-ur-Rehman.3rd National conference on Pre-clinical and clinical researches on Products of Biological origin In Hospitals, Abstract, (17th April 2004).